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書籍

GREEN'S PROTECTIVE GROUPS in Organic Synthesis 4th Edition グリーンの保護基第4版

GREEN'S PROTECTIVE GROUPS in Organic Synthesis, 4th Edition グリーンの保護基第4版
GREEN'S PROTECTIVE GROUPS in Organic Synthesis,
4th Edition
グリーンの保護基第4版

Peter G. M. Wuts, Theodora W. Greene

ISBN: 978-0-471-69754-1
Hardcover
1082 pages
November 2006
$115.00

解説/DESCRIPTION

7年ぶりの改訂版!
Green's Protective Groups in Organic Synthesisは、 有機合成で使われる保護基に関する書籍としては唯一の専門書です。様々な保護や脱保護に関し、多くの技術が紹介され、また反応チャートを参考に保護基の選択や脱保護の順序などを研究に役立てることが可能です。第4版は1350の保護基や、主要文献への8000以上ものリファレンスを含んだ最新情報が満載です。本書は有機合成、医薬科学者必須の一冊です。
  • フルオラスファミリーなど、新たな保護基を数多く掲載
  • 新たなクリーベイジ法や多くのクラッシックな保護基を紹介
  • 保護基の反応でよきの難しい再度リアクションをカバー
  • シリルエーテルの脱保護を含む最新チャートを満載
  • 1998年〜2005年までに発表された新しい3100の参考論文を収録

目次/TABLE OF CONTENTS

Preface to the Fourth Edition.
Preface to the Third Edition.

Preface to the Second Edition.

Preface to the First Edition.

Abbreviations.

1. The Role of Protective Groups in Organic Synthesis.

2. Protection for the Hydroxyl Group, Including 1,2- and 1,3-Diols.

Ethers.

Esters.

Protection for 1,2- and 1,3-Diols.

3. Protection for Phenols and Catechols.

Protection for Phenols.

Ethers.

Silyl Ethers.

Esters.

Carbonates.

Aryl Carbamates.

Phosphinates.

Sulfonates.

Protection for Catechols.

Cyclic Acetals and Ketals.

Cyclic Esters.

Protection for 2-Hydroxybenzenethiols.

4. Protection for the Carbonyl Group.

Acetals and Ketals.

Miscellaneous Derivatives.

Monoprotection of Dicarbonyl Compounds.

5. Protection for the Carboxyl Group.

Esters.

Amides and Hydrazides.

Protection of Boronic Acids.

Protection of Sulfonic Acids.

6. Protection for the Thiol Group.

Thioethers.

Thioesters.

Miscellaneous Derivatives.

7. Protection for the Amino Group.

Carbamates.

Amides.

Special-NH Protective Groups.

Protection for Imidazoles, Pyrroles, Indoles, and other Aromatic Heterocycles.

Protection for the Amide ?NH.

Protection for the Sulfonamide ?NH.

8. Protection for the Alkyne -CH.

9. Protection for the Phosphate Group.

Some General Methods for Phosphate Ester Formation.

Removal of Protective Groups from Phosphorus.

Alkyl Phosphates.

Phosphates Cleaved by Cyclodeesterifi cation.

Benzyl Phosphates.

Phenyl Phosphates.

Photochemically Cleaved Phosphate Protective Groups.

Amidates.

Miscellaneous Derivatives.

10. Reactivities, Reagents, and Reactivity Charts.

Reactivities.

Reagents.

Reactivity Charts.

1 Protection for the Hydroxyl Group: Ethers.

2 Protection for the Hydroxyl Group: Esters.

3 Protection for 1,2- and 1,3-Diols.

4 Protection for Phenols and Catechols.

5 Protection for the Carbonyl Group.

6 Protection for the Carboxyl Group.

7 Protection for the Thiol Group.

8 Protection for the Amino Group: Carbamates.

9 Protection for the Amino Group: Amides.

10 Protection for the Amino Group: Special ?NH Protective Groups.

11 Selective Deprotection of Silyl Ethers.

Index.