
Arterial Disease of the Leg Frequently Overlooked in Patients with Heart Disease
Coronary artery disease (CAD) is prevalent in patients with peripheral arterial disease (PAD) and it is known that PAD is under diagnosed in the primary care setting, but a new study found that it is often overlooked even in patients with known heart disease who are under a cardiologist’s care. The study was published in the May issue of Catheterization and Cardiovascular Interventions, the official journal of The Society for Cardiovascular Angiography and Interventions (SCAI).
Results at a Glance:
- Approximately one out of six patients had previously unrecognized PAD, despite being under the care of a cardiovascular specialist.
- Most patients with PAD did not limp or have leg pain, two symptoms of the disease. “The combination of physician lack of awareness and lack of symptoms among patients results in failure to diagnose PAD, even in patients who are at high risk,” the researchers state. “Furthermore, clinical evaluation alone often lacks the sensitivity and specificity to optimally identify PAD particularly in less advanced stages and in hospitalized patients with CAD.”
- Missed PAD was more frequent in older patients and women, which goes against the conventional wisdom that PAD is more prevalent in men and suggests that PAD is more frequently overlooked in women than men in outpatient settings.
To read the complete study and results, click here.
Many physicians cite the lack of space, time and resources as barriers to implementing a systematic PAD screening program, however new guidelines by the American Heart Association and the American College of Cardiology advocate screening for PAD in patients with CAD. The authors conclude that their findings present a compelling argument that screening for PAD should become standard of care in these patients.
Interested in more PAD studies? Then check out:
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Clinical Question:
Does dronedarone improve clinical outcomes in high risk patients with atrial fibrillation?
Bottom Line:
Dronedarone will prevent 1 hospitalization for every 14 high-risk, older patients with intermittent atrial fibrillation treated for 2 years. There is no impact on all-cause mortality, and adverse effects were more common in the dronedarone group.
Read the complete POEM synopsis.
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ICD therapy underutilized; with recent data showing greater under use in minorities & women
By Eric Prystowsky, MD
Editor-in-Chief of Journal of Cardiovascular Electrophysiology (JCE)
Few issues in cardiology have undergone as many randomized clinical trials as has the implantable defibrillator (ICD). These data have demonstrated that the ICD is a powerful therapy to prevent sudden cardiac death and reduce overall mortality, especially in patients with heart failure and substantial reductions in left ventricular function.
Yet, this valuable therapy continues to be markedly underutilized, with most estimates suggesting about 15-20% of eligible patients being offered an ICD. To make matters worse, recent data show even greater under use in minorities and women. Further, recent studies have demonstrated a great disparity among physicians in prescribing a cardiac resynchronization ICD that not only can reduce mortality, but can substantially reduce the symptoms of heart faiure.
So, as the poet said, we truly have miles to go before we "rest" on this lack of patient care, and the JCE will continue to publish scientific studies in this area of research and hopefully care will improve soon".

Find interesting and thought-provoking articles about ICD therapy online, like the articles featured below, online at www.wiley.com/go/cardiology
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Free access to featured articles ends 6/30/09!
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Online submission site launched for the Journal of Clinical Hypertension (JCH)
Reach more than 42,000 cardiologists, internists, and family physicians in this ISI and MEDLINE indexed publication! Visit our new online submission site to submit your paper today.
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Paclitaxel-induced ST-Segment Elevations
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